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Diptoindonesin G
CAS No. 1190948-58-3
Diptoindonesin G ( Dip G )
产品货号. M10656 CAS No. 1190948-58-3
A natural compound, novel chemical probe reciprocally stabilizes ERβ and destabilizes ERα in breast cancer cells.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥7857 | 有现货 |
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| 50MG | ￥16038 | 有现货 |
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| 100MG | ￥20250 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Diptoindonesin G
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A natural compound, novel chemical probe reciprocally stabilizes ERβ and destabilizes ERα in breast cancer cells.
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产品描述A natural compound, novel chemical probe reciprocally stabilizes ERβ and destabilizes ERα in breast cancer cells; targets CHIP ubiquitin E3 ligase to modulate ER protein stability, enhances the transcription and anti-proliferative activities of ERβ, while attenuating the transcription and proliferative effects of ERα; the first small molecule that can restore the balance of ERα and ERβ.
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同义词Dip G
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通路Endocrinology/Hormones
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靶点Estrogen Receptor/ERR
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受体Estrogen Receptor/ERR
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研究领域——
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适应症——
化学信息
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CAS Number1190948-58-3
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分子量360.32
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分子式C21H12O6
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C1C2=C3C(OC(C4=CC=C(O)C=C4)=C3C5=C1C(O)=CC(O)=C5)=CC(O)=C2
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化学全称4,7,9-trihydroxy-1-(4-hydroxyphenyl)-6H-anthra[1,9-bc]furan-6-one
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Zhao Z, et al. Chem Biol. 2015 Dec 17;22(12):1608-21.
2. Juliawaty LD, et al. Nat Prod Commun. 2009 Jul; 4(7):947-50.
3. Gao J, et al. Cell Death Dis. 2017 May 4;8(5):e2765.
2. Juliawaty LD, et al. Nat Prod Commun. 2009 Jul; 4(7):947-50.
3. Gao J, et al. Cell Death Dis. 2017 May 4;8(5):e2765.
产品手册
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